ABO Rh Typing - Revision history

Admin at 21:20, 13 February 2025

2025-02-13T21:20:28Z

← Older revision		Revision as of 17:20, 13 February 2025
Line 86:		Line 86:
	\| colspan="2" \|None		\| colspan="2" \|None
	\|-		\|-
	\|Group O		\| rowspan="3" \|Group O
	\|Anti-A		\|Anti-A
	~~Anti-B~~
	~~Anti-A,B~~
	\|IgM		\|IgM
	IgM		\|-
	IgG		\|Anti-B
			\|IgM
			\|-
			\|Anti-A,B
			\|IgG
	\|}		\|}
	IgG antibodies can cross placenta, but IgM usually doesn't (except in trauma)		IgG antibodies can cross placenta, but IgM usually doesn't (except in trauma)

			=== Secretory Status ===

			* A, B, and H antigens can be soluble
			* Se gene confers secretory status
			** Dominant gene (FUT-2)
			** Fucose added to type 1 precursor
			*** Type 1 precursor found in body fluids and secretions
			*** Type 2 precursor found on RBCs, body fluids, and secretions
			** H antigen is then secreted, as are any A and B antigens attached to it

	ABO Typing		ABO Typing
	* Babies: perform forward testing ONLY		* Babies: perform forward testing ONLY

Admin at 21:11, 13 February 2025

2025-02-13T21:11:21Z

← Older revision		Revision as of 17:11, 13 February 2025
Line 23:		Line 23:
	** Precursor to A and B antigens		** Precursor to A and B antigens
	* H allele frequency >99.99%		* H allele frequency >99.99%
	** hh is Bombay phenotype		** hh is Bombay phenotype (O<sub>h</sub>)
	*** Produces anti-H antibodies		*** Produces anti-H antibodies
			*** Appears as Group O on T&S, but antibody screens and panels will be fully positive

	ABO Antigens		ABO Antigens
Line 35:		Line 36:
	\|+		\|+
	!		!
			!hh
	!H		!H
	!A		!A
Line 40:		Line 42:
	\|-		\|-
	\|Gene Product (Enzyme)		\|Gene Product (Enzyme)
			\|None
	\|L-fucosyltransferase		\|L-fucosyltransferase
	\|N-acetylgalactosaminyltransferase		\|N-acetylgalactosaminyltransferase
Line 45:		Line 48:
	\|-		\|-
	\|Dominant/Terminal Sugar		\|Dominant/Terminal Sugar
			\|None (only precursor)
	\|L-fucose		\|L-fucose
	\|N-acetyl-galactosamine		\|N-acetyl-galactosamine
Line 50:		Line 54:
	\|-		\|-
	\|Groups		\|Groups
			\|O<sub>h</sub> (Bombay)
	\|A, B, AB, O		\|A, B, AB, O
	\|A, AB		\|A, AB

Admin at 15:41, 13 February 2025

2025-02-13T15:41:17Z

@@ Line 1: / Line 1: @@
 The ABO system is the most clinically significant blood group system in transfusion medicine.
@@ Line 93: / Line 94: @@
 * Babies: if baby appears Rh Negative and the mother is Rh Negative, perform weak D testing
 * AB Rh Positive patients require Rh Control to be performed
-** RHC should be a '''reaction of''' '''0'''. This checks that the agglutination seen is '''not''' a result of autoagglutination in the patient.
+** RHC should be a '''reaction of''' '''0'''. This checks that the agglutination seen is '''not''' a result of auto-agglutination in the patient.
 * Rh Control is also used for discrepancies (Rh testing results don't match, e.g. Anti-D1 is 2+ and Anti-D2 is 0)
 * Rh Control is also used for IAT Testing (e.g., Weak D testing)

Admin at 04:14, 13 February 2025

2025-02-13T04:14:00Z

@@ Line 53: / Line 53: @@
 |B, AB
 |}
 ABO Typing
 * Babies: perform forward testing ONLY

Admin at 04:22, 12 February 2025

2025-02-12T04:22:32Z

@@ Line 10: / Line 10: @@
 * A and B genes present on chromosome 9
 * A and B co-dominant, O is recessive
 * One allele received from each parent
 ABO Typing
 * Babies: perform forward testing ONLY

Admin at 18:08, 11 February 2025

2025-02-11T18:08:28Z

← Older revision		Revision as of 14:08, 11 February 2025
Line 1:		Line 1:
			The ABO system is the most clinically significant blood group system in transfusion medicine.

			* Carbohydrate antigens
			* Non-RBC stimulated: individuals possess ABO antibodies to the antigens that they lack
			* IgM
			* Cause severe transfusion reactions
			** Cell lysis and hemolysis

			ABO Genes

			* A and B genes present on chromosome 9
			* A and B co-dominant, O is recessive
			* One allele received from each parent

			ABO Typing
	* Babies: perform forward testing ONLY		* Babies: perform forward testing ONLY
	* Babies: if baby appears Rh Negative and the mother is Rh Negative, perform weak D testing		* Babies: if baby appears Rh Negative and the mother is Rh Negative, perform weak D testing

Admin: 1 revision imported

2024-02-20T16:12:16Z

1 revision imported

← Older revision	Revision as of 12:12, 20 February 2024
(No difference)

MedLabWIki>Admin: Created page with "* Babies: perform forward testing ONLY * Babies: if baby appears Rh Negative and the mother is Rh Negative, perform weak D testing * AB Rh Positive patients require Rh Control to be performed ** RHC should be a '''reaction of''' '''0'''. This checks that the agglutination seen is '''not''' a result of autoagglutination in the patient. * Rh Control is also used for discrepancies (Rh testing results don't match, e.g. Anti-D1 is 2+ and Anti-D2 is 0) * Rh Control is also use..."

2023-11-22T23:50:31Z

Created page with "* Babies: perform forward testing ONLY * Babies: if baby appears Rh Negative and the mother is Rh Negative, perform weak D testing * AB Rh Positive patients require Rh Control to be performed ** RHC should be a '''reaction of''' '''0'''. This checks that the agglutination seen is '''not''' a result of autoagglutination in the patient. * Rh Control is also used for discrepancies (Rh testing results don't match, e.g. Anti-D1 is 2+ and Anti-D2 is 0) * Rh Control is also use..."

New page

* Babies: perform forward testing ONLY
* Babies: if baby appears Rh Negative and the mother is Rh Negative, perform weak D testing
* AB Rh Positive patients require Rh Control to be performed
** RHC should be a '''reaction of''' '''0'''. This checks that the agglutination seen is '''not''' a result of autoagglutination in the patient.
* Rh Control is also used for discrepancies (Rh testing results don't match, e.g. Anti-D1 is 2+ and Anti-D2 is 0)
* Rh Control is also used for IAT Testing (e.g., Weak D testing)